Isoxazoline Herbicides

Highly enantioselective synthesis of isoxazoline N-oxides.

The reaction of cinchonidine (cinchonine)-derived ammonium salts with nitroolefins in the presence of Cs2CO3 to afford optically active isoxazoline N-oxides with excellent ee and high de values has been developed.

Mosquitocidal Activity and Mode of Action of the Isoxazoline Fluralaner

Mosquitoes, such as Aedes aegypti and Anopheles gambiae, are important vectors of human diseases. Fluralaner, a recently introduced parasiticide, was evaluated as a mosquitocide in this study. On Ae. aegypti and An. gambiae fourth-instar larvae, fluralaner had 24-h LC50 (lethal concentration for 50% mortality) values of 1.8 ppb and 0.4 ppb, respectively. Following topical application to adult A...

Mode of action of a new isoxazoline compound

A new isoxazoline compound (5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3(3-methylthiophen-2-yl)-1,2-isoxazoline; code name, EK-5229) was reported to have safety in rice and control barnyardgrass (Echinochloa crus-galli), but its mode of action was unknown. The compound did not inhibit germination of sensitive grasses, but it inhibited further growth. The symptom was primarily stunting and discolo...

The Effect of Herbicides

Although some work has been done on the effect of 2,4-dichlorophenoxyacetic acid (2,4-D) on the numbers and kinds of organisms of the soil (Smith, Dawson and Wenzel, 1945; Hoover and Colmer, 1953), on respiration of certain soil organisms (Magee, 1954), and on the effect of this herbicide on certain processes of the soil (Newman, 1947; Jones, 1948; Carlyle and Thorpe, 1947; and Payne and Fults,...

Herbicides in Aquatic Systems